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Chronic Beryllium Disease

Overview

慢性铍病(简称CBD)会导致肺部组织出现疤痕. 当一个人吸入灰尘或铍的烟雾(一种自然产生的轻质材料)并对这种材料敏感时,就会发生这种情况. Beryllium is used in various industries, such as electronics, aerospace, dental, atomic energy and defense.

Our approach to chronic beryllium disease

加州大学旧金山分校为与工作有关的肺部疾病提供全面的评估和护理, such as chronic beryllium disease. 我们提供广泛的肺功能测试以及灵活的支气管镜检查气道.

Although chronic beryllium disease currently has no cure, 治疗可以防止肺部进一步形成疤痕,并改善血液中的含氧量. 其中包括抑制免疫系统对铍的反应的药物和提供补充氧气的设备. 我们的目标是减缓疾病的进展,帮助我们的病人感觉更好.

Lung transplantation may be an option for severe cases. UCSF is currently the top lung transplant program in the U.S. 高于预期的患者存活率和移植物存活率(移植肺的持续功能).

Awards & recognition

  • usnews-neurology

    Among the top hospitals in the nation

  • usnews-pulmonology

    No. 8 in the nation for pulmonology & lung surgery

Signs & symptoms

在早期阶段,CBD可能不会引起任何明显的症状. However, over time, the following symptoms may develop:

  • Shortness of breath with physical activity
  • Dry cough that will not go away
  • Fatigue
  • Night sweats
  • Chest and joint pain
  • Loss of appetite

Diagnosis

In making a diagnosis of chronic beryllium disease, 你的十大赌博平台排行榜会记录你详细的病史和职业史,并进行彻底的体检. 这将有助于确定你是否接触过任何可能导致CBD或其他职业性肺病的有毒物质. CBD,没有特定的职业史和专门的测试,是相同的疾病 sarcoidosis and therefore is often misdiagnosed as that condition.

诊断CBD的另一个重要步骤是一种简单的血液检查,称为铍淋巴细胞增殖试验(BeLPT)。. 这个测试可以确定你的免疫系统是否对铍有反应,这可能是指CBD. If you test positive for this test, 可进行其他检查以作出明确诊断:

  • Chest X-ray. A chest X-ray may be taken to look for any abnormalities in your lungs.
  • Pulmonary function testing (PFT). This test 包括一系列的呼吸动作,测量你肺部的气流和空气量, 这样十大赌博平台排行榜就能客观地评估你的肺功能了.
  • High resolution computed tomography (HRCT). This is a special type of CT scan 这为你的十大赌博平台排行榜提供了你肺部的高分辨率图像. 这些图像对于确定你患有哪种类型的职业性肺病非常有价值. Having a HRCT is no different than having a regular CT scan; they both are performed on an open-air table and take only a few minutes.
  • Bronchoscopy. This test involves passing a flexible fiberoptic scope, about the diameter of a pencil, 进入肺部获取液体和组织样本以帮助诊断. In evaluating CBD, 支气管镜检查通常包括对患者的痰液进行检查,因为痰液可以进行与血液相同的铍淋巴细胞增殖试验(BeLPT).
  • Lung biopsy. 如果患者的胸部x光或高分辨率计算机断层扫描(HRCT)检测到任何生长或异常, 肺活检可用于确定是否存在肺癌. 肺活组织检查是一种外科手术,从肺组织标本中取样并在显微镜下检查.

Treatments

此时,还没有治愈慢性铍病的方法. However, 治疗方法可以帮助减缓疾病的进展, prevent further lung damage caused by scarring, improve oxygen levels in the bloodstream and manage symptoms.

治疗取决于您的疾病和症状的严重程度,可能包括以下内容:

Immunospressive drugs

强的松是最常用于CBD患者的免疫抑制药物. 强的松减缓免疫系统对肺部铍的反应,有助于减轻症状,同时改善肺部和血液之间的气体交换. 患者通常给予一个疗程的强的松,在一段时间内逐渐减少. Over time, however, prednisone can cause side effects. 在开始治疗前与十大赌博平台排行榜讨论这些副作用是很重要的.

Oxygen therapy

As the disease progresses, 患者可能会发现自己呼吸越来越困难,可能需要补充氧气. 治疗通过三个系统提供:浓缩器、压缩气体系统和液体系统. 最能满足你需要的系统取决于你疾病的严重程度, lifestyle and where you live. 每个系统都有自己的优点和缺点,你应该和你的十大赌博平台排行榜讨论.

Oxygen can be delivered by a number of devices, such as a small plastic tube placed under the nostrils, called a cannula, facemask and Transtracheal Oxygen Catheter, 是一根放在脖子上的细管,直接将氧气输送到气管. 该设备用于连续、长期的氧疗.

Lung transplant

In severe cases, lung transplant may be recommended.

加州大学旧金山分校健康医学专家已经审查了这些信息. 它仅用于教育目的,并不打算取代您的十大赌博平台排行榜或其他医疗保健提供者的建议. 我们鼓励您与您的供应商讨论您可能遇到的任何问题或疑虑.

Recommended reading

FAQ: Lung Transplant

Common questions regarding lung transplants including, how it will change a patient's life, how long the waiting list is, potential complications and more.

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